IAP Infectious Diseases Chapter has always strived to maintain high academic standard and update the members. Clinical Grand Rounds in Pediatric Infectious Diseases is another endeavor and this is in its second edition. This book will enrich the knowledge of a practicing pediatrician and incite the inquisitiveness in a student. The earnest effort by the editors and sincere contribution by the authors are appreciable as every page and every case opens a new window to the clinical world which is sometime unique, sometime unexplored and often revealing.