The Minibus rides again! When Secret Wars reshapes the cosmos, Shiklah - Mrs. Deadpool herself - takes center stage (with her groovy ghoulies) in a world without Wade Wilson! Then, the Merc returns for a pair of showdowns with the Mad Titan and the Ragin' Cajun! Can Deadpool win in a deadly love triangle with Thanos? And will he survive one last job with his long-time con-job partner Gambit? Best frenemies Deadpool and Cable rub shoulders and trade bullets once more when Nathan is tasked with keeping one man alive - the same guy Wade has been hired to off! And, when Forbush Man is murdered, can Deadpool stop a serial killer from offing all Marvel's funniest characters?